Ionomycin is derived from Streptomyces conglobatus, and is a noted calcium ionophore with a selectivity of Pb2+ > Cd2+ > Zn2+ > Mn2+ > Ca2+ > Mg2+ >> Sr2+ ~ Ba2+. There is almost no binding to Sr2+ or Ba2+ or to monovalent alkali metal cations.
Study the effect of this compound on planar phospholipid bilayers with tethered membrane preparations.
- Characterization of ionomycin as a calcium ionophore. C Liu and T E Hermann, The Journal of Biological Chemistry, 253, 5892-5894, 1978.
- Ca2+ transport properties of ionophores A23187, ionomycin, and 4-BrA23187 in a well defined model system. W.L. Erdahl, C.J. Chapman, R.W. Taylor and D.R. Pfeiffer, Biophysical Journal, 66, 1678-1693, 1994. DOI:10.1016/S0006-3495(94)80959-2
- Ionomycin, a Carboxylic Acid Ionophore, Transports Pb2+ with High Selectivity. Warren L. Erdahl, Clifford J. Chapman, Richard W. Taylor and Douglas R. Pfeiffer, Journal of Biological Chemistry, 275, 7071-7079, 2000. DOI: 10.1074/jbc.275.10.7071
This product is intended for in vitro research and educational experiments. It is not suitable for clinical purposes and is not for human or veterinary use. Made by BioAustralis Sydney, Australia.
- Quantity: 1 mg
- Purity: > 95%